The Golgi Apparatus: Morphology and Function with Recent Facts
نویسندگان
چکیده
منابع مشابه
Kinases regulating Golgi apparatus structure and function.
Protein kinases control Golgi function in both mitotic and interphase cells. In mitosis, phosphorylation of structural proteins by Cdk1 (cyclin-dependent kinase 1)-cyclin B, Polo-like and mitogen-activated protein kinases underlie changes in Golgi reorganization during cell division. While in interphase, signalling pathways that are associated with the Golgi control secretory function through a...
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Ríos et al. (2004) report in this issue that the Golgi protein GMAP-210 is sufficient to confer pericentrosomal positioning and recruits gamma-tubulin and associated microtubule-nucleating ring complex proteins to Golgi membranes. The results raise the possibility that short microtubules emanate from the Golgi to mediate its organization and positioning.
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At some point in their lives all cells need to grow and divide. In eukaryotic cells these processes require the delivery of new proteins and lipids from their site of synthesis in the endoplasmic reticulum (ER) to the cell surface. The Golgi apparatus, first visualised under the light microscope in 1898 by Camillo Golgi using a staining method he had developed to study neurons, lies on the rout...
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Most models put forward to explain cellular processes do not stand the test of time. The 'lucky' few that are able to survive extensive experimental tests and peer critique may eventually become dogmas or paradigms. When this happens, the amount of experimental data required to overturn the paradigm is extensive. To some, such inertia may seem prohibitive to scientific progress but rather, in o...
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In general, the basic principles of trafficking systems in plant cells appear to be similar to those in animal and yeast cells, indicating that trafficking mechanisms arehighly conserved throughout all eukaryotes (Jurgens, 2004; Vitale and Hinz, 2005). However, there are still considerable variations at the molecular level as well as in applying these basic principles to situations in plant cel...
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ژورنال
عنوان ژورنال: Bezmialem Science
سال: 2019
ISSN: 2148-2373
DOI: 10.14235/bas.galenos.2019.2806